Elsevier/North-Holland Biomedical Press VISUAL STIMULATION INCREASES REG IO N A L CEREBRAL BLOOD FLOW AND METABOLISM IN THE GOLDFISH
نویسندگان
چکیده
SUMMARY Studies with radioactive antipyrene and deoxyglucose indicate that both blood flow and metabolism are enhanced in the goldfish optic tectum following a brief visual stimulation. It is concluded that the brain of cold-blooded animals demonstrates regionally regulated physiological alterations, previously reported only in warm-blooded species.
منابع مشابه
BOLD-Perfusion Coupling during Monocular and Binocular Stimulation
Previous studies have suggested that during selective activation of a subset of the zones comprising a columnar system in visual cortex, perfusion increases uniformly in all columns of the system, while increases in oxidative metabolism occur predominantly in the activated columns. This could lead to disproportionately large blood oxygenation level-dependent (BOLD) signal increases for a given ...
متن کاملIncreases in oxygen consumption without cerebral blood volume change during visual stimulation under hypotension condition.
The magnitude of the blood oxygenation level-dependent (BOLD) signal depends on cerebral blood flow (CBF), cerebral blood volume (CBV) and cerebral metabolic rate of oxygen (CMRO2). Thus, it is difficult to separate CMRO2 changes from CBF and CBV changes. To detect the BOLD signal changes induced only by CMRO2 responses without significant evoked CBF and CBV changes, BOLD and CBV functional mag...
متن کاملInvestigating the metabolic changes due to visual stimulation using functional proton magnetic resonance spectroscopy at 7 T.
Proton magnetic resonance spectroscopy ((1)H-MRS) has been used to demonstrate metabolic changes in the visual cortex on visual stimulation. Small (2% to 11%) but significant stimulation induced increases in lactate, glutamate, and glutathione were observed along with decreases in aspartate, glutamine, and glycine, using (1)H-MRS at 7 T during single and repeated visual stimulation. In addition...
متن کاملHemodynamic changes after visual stimulation and breath holding provide evidence for an uncoupling of cerebral blood flow and volume from oxygen metabolism.
Functional neuroimaging is most commonly performed using the blood-oxygenation-level-dependent (BOLD) approach, which is sensitive to changes in cerebral blood flow (CBF), cerebral blood volume (CBV), and the cerebral metabolic rate of oxygen (CMRO(2)). However, the precise mechanism by which neuronal activity elicits a hemodynamic response remains controversial. Here, visual stimulation (14 se...
متن کاملChanges in cerebral arterial, tissue and venous oxygenation with evoked neural stimulation: implications for hemoglobin-based functional neuroimaging.
Little is known regarding the changes in blood oxygen tension (P(O2)) with changes in brain function. This work aimed to measure the blood P(O2) in surface arteries and veins as well as tissue with evoked somato-sensory stimulation in the anesthetized rat. Electrical stimulation of the forepaw induced average increases in blood flow of 44% as well as increases in the tissue P(O2) of 28%. More i...
متن کامل